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Other trade names: Bactrim, Apo-Sulfatrim, Apo-Sulfatrim DS, Bactrim DS, Bactrim I.V., Bactrim Pediatric, Co-trimoxazole, Cofatrim Forte, Coptin, Coptin 1, Cotrim, Cotrim DS, Cotrim Pediatric, Cotrimazine, Cotrimoxazole, Novo-Trimel, Novo-Trimel D.S., Nu-Cotrimox, Nu-Cotrimox DS, Roubac, SMZ-TMP, Septra, Septra DS, Septra Grape Suspension, Septra I.V., Septra Suspension, Sulfatrim, Sulfatrim Pediatric, Sulfatrim S/S, Sulfatrim Suspension, Sulfatrim-DS, Sulfamethoxazole, Trimethoprim, Bactrim.
International name - Co-trimoxazole
Bactrim – is an antimicrobial combined agent.
Pharmacological action:
This combined agent consists of sulfamethoxazole and trimethoprim. It is a bactericidal drug of broad-spectrum, active against the following microorganisms: Streptococcus spp., Staphylococcus spp., Streptococcus pneumoniae, Neisseria meningitidis, Neisseria gonorrhoeae, Escherichia coli, Salmonella spp., Vibrio cholerae, Bacillus anthracis, Haemophilus influenzae etc. It inhibits vital functions of Escherichia coli, which leads to a reduction of thiamine, riboflavin, nicotinic acid synthesis and other vitamins of B-group in an intestine. The duration of the therapeutic effect - 7 hours.
Proposed clinical use:
pyelonephritis, prostatitis, cystitis, pyelitis, urethritis, venereal granuloma, bronchitis, multiple bronchiectasis, croupous pneumonia, sinusitis, laryngitis, tonsillitis, otitis media, typhoid, dysentery, cholecystitis, acne and furunculosis, osteomyelitis, malaria and toxoplasmosis.
